The MPS Research Laboratory is dedicated to treatment of mucopolysaccharidoses, a group of inherited lysosomal storage diseases.

About the MPS Research Lab

Hanley-Hardison Building at LA BioMed

The MPS Research Laboratory is part of the Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center. We are a translational research laboratory specializing in enzyme replacement therapy for mucopolysaccharidosis (MPS).

WORLD Abstracts and Presentations

MPS Research Lab activities will be presented at the annual WORLD Lysosomal Disease Network meeting in Miami, Florida on February 10-12.

Dr. Matthew Ellinwood of Iowa State University will present work performed in collaboration with us on treatment of the brain using intravenous and intrathecal enzyme replacement therapy for MPS I, during the afternoon session on Wednesday Feb. 10.

Legends of Golf Tournament

From the CuretheProcess.org newsletter:

Research Challenges in CNS Manifestations of Inborn Errors of Metabolism

The National Institutes of Health (Office of Rare Diseases Research, and National Institute of Neurologic Disorders and Stroke) and the Food and Drug Administration (Center for Drug Evaluation and Research, Division of Gastroenterology Products) are sponsoring a workshop on Research Challenges in CNS Manifestations of Inborn Errors of Metabolism to be held December 7 and 8 in Bethesda, Maryland.

MPS Walk/Run Los Angeles

From Tami Slawson:

The 9th Annual National MPS Society’s Walk and Run LA is October 17th 2009 is at Oak Mesa Park in La Verne, CA (click here for directions). Please join us for this worthwhile event. All proceeds raised benefit research for children with MPS/ML and related disorders. We will again be hosting the family picnic after the walk/run for all of our MPS/ML families.

You can register online here.

ASHG 2009 -- Abstracts by the MPS Research Lab

The American Society of Human Genetics Meeting is coming up (click here for more info), and the MPS Research Lab is presenting four posters on our research.

Dr. Brigette Tippin will present work on in vitro studies of fluorescent-labeled iduronidase (poster #1033), which has potential applications in tracking the movement of exogenously adminsitered enzyme in vivo. (click "Read More" to continue)

Continuous enzyme therapy is inferior to weekly

This week's Journal of Inherited Metabolic Disease contains a Short Report from the MPS Research Lab. The jist of the report is that treatment with the enzyme replacement therapy for MPS I (Aldurazyme) works better when it's given once a week than if it's given around the clock by infusion pump.

Click here for the PubMed link.

LA BioMed on Facebook

The Los Angeles Biomedical Research Institute at Harbor-UCLA (our research institute) is on Facebook!

Click here to visit their facebook page. Login and become a fan to join.

This will allow you to receive important announcements and informtion about LA Biomed.

MPS Research Laboratory to Present Posters at ICIEM

The MPS Research Laboratory will present the following posters at the 11th ICIEM meeting in San Diego August 28 - September 2, 2009.

S Shah, NM Ellinwood, A Dierenfeld, M McEntee, J Jens, E Snella, WA Ware, L Moran, M Passage, S Le, P Dickson. Intravenous enzyme replacement therapy improves cardiac valvular storage in MPS I dogs treated from birth (poster 395)

PI Dickson, NM Ellinwood, S Hanson, C Vite, M Passage, S Le, C Guerra. Intrathecal enzyme replacement therapy may stabilize or reverse signs of spinal cord compression in MPS I dogs (poster 394)

Hope to see you there!

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